Product Data Sheet
K2-B4-5e
Catalog No. A40321
K2-B4-5e is an E3 ligase KLHDC2-based degrader targeting BRD4 and the androgen receptor (AR). This compound effectively induces rapid and robust degradation of BET family proteins and AR within cellular environments. K2-B4-5e holds potential for applications in research focused on cancer biology and androgen signaling pathways.
Chemical Information
| Catalog Num | A40321 |
|---|---|
| M. Wt | 949.51 |
| Formula | C52H49ClN8O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3093556-90-9 |
| Synonyms | |
| SMILES | O=C(C[C@@H]1N=C(C2=C(N3C(C)=NN=C13)SC(C)=C2C)C4=CC=C(C=C4)Cl)NC5=CC=C(C=C5)C6=CC=C(C=C6)C(N7CCC8=C(N(C(C(CC(C)C)=C8)=O)C9=CN(C(C=C9)=O)CC(OC)=O)C7)=O |
Biological Activity
| Description | K2-B4-5e is an E3 ligase KLHDC2-based degrader targeting BRD4 and the androgen receptor (AR). This compound effectively induces rapid and robust degradation of BET family proteins and AR within cellular environments. K2-B4-5e holds potential for applications in research focused on cancer biology and androgen signaling pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
