Product Data Sheet
TAT-PiET-PROTAC
Catalog No. A40334
TAT-PiET-PROTAC is a BRD4 inhibitor designed as a proteolysis-targeting chimera (PROTAC) that incorporates the cell-penetrating peptide TAT-PiET. This compound effectively reduces the levels of BRD4 and JMJD6, demonstrating significant inhibition of cell proliferation. TAT-PiET-PROTAC is particularly relevant for investigating endocrine resistance in ERα-positive breast cancer cells, making it a valuable tool for cancer research.
Chemical Information
| Catalog Num | A40334 |
|---|---|
| M. Wt | 3430.01 |
| Formula | C151H250N54O36S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3036046-04-2 |
| Synonyms | |
| SMILES |
Biological Activity
| Description | TAT-PiET-PROTAC is a BRD4 inhibitor designed as a proteolysis-targeting chimera (PROTAC) that incorporates the cell-penetrating peptide TAT-PiET. This compound effectively reduces the levels of BRD4 and JMJD6, demonstrating significant inhibition of cell proliferation. TAT-PiET-PROTAC is particularly relevant for investigating endocrine resistance in ERα-positive breast cancer cells, making it a valuable tool for cancer research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
