Product Data Sheet
(2S,3R)-LP99
Catalog No. A40337
(2S,3R)-LP99 is a highly selective inhibitor of BRD7 and BRD9, exhibiting a KD of 99 nM for BRD9. This compound effectively disrupts the binding of BRD7 and BRD9 to acetylated histones both in vitro and in cellular environments. (2S,3R)-LP99 is instrumental for research into the regulatory roles of BRD7 and BRD9 in pro-inflammatory cytokine secretion, making it a valuable tool for studies investigating inflammation and epigenetic regulation.
Chemical Information
| Catalog Num | A40337 |
|---|---|
| M. Wt | 516.05 |
| Formula | C26H30ClN3O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1808948-28-8 |
| Synonyms | |
| SMILES | CC(CS(=O)(N[C@@H]([C@@H](N1C2=CC3=C(C(C)=CC(N3C)=O)C=C2)C4=CC=C(C=C4)Cl)CCC1=O)=O)C |
Biological Activity
| Description | (2S,3R)-LP99 is a highly selective inhibitor of BRD7 and BRD9, exhibiting a KD of 99 nM for BRD9. This compound effectively disrupts the binding of BRD7 and BRD9 to acetylated histones both in vitro and in cellular environments. (2S,3R)-LP99 is instrumental for research into the regulatory roles of BRD7 and BRD9 in pro-inflammatory cytokine secretion, making it a valuable tool for studies investigating inflammation and epigenetic regulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
