Product Data Sheet
BRD4 D1-IN-1
Catalog No. A40355
BRD4 D1-IN-1 is a selective inhibitor of the BRD4 D1 domain, demonstrating an IC50 of less than 0.092 µM and an affinity of 18 nM. This compound exhibits over 500-fold selectivity for BRD4 D1 compared to BRD2 D1 and BRD4 D2, as determined by isothermal titration calorimetry (ITC). BRD4 D1-IN-1 is primarily used in research related to cancer and inflammatory diseases, providing insights into the role of BRD4 in transcriptional regulation.
Chemical Information
| Catalog Num | A40355 |
|---|---|
| M. Wt | 578.67 |
| Formula | C32H37F3N6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2863623-98-5 |
| Synonyms | |
| SMILES | CC(C1=CC=C(C(OC2=NC(C3=C(N=CN3[C@@H]4CN(CC4)CCN(C)C)C5=CC=C(C=C5)C(F)(F)F)=CC=N2)=C1)C)C |
Biological Activity
| Description | BRD4 D1-IN-1 is a selective inhibitor of the BRD4 D1 domain, demonstrating an IC50 of less than 0.092 µM and an affinity of 18 nM. This compound exhibits over 500-fold selectivity for BRD4 D1 compared to BRD2 D1 and BRD4 D2, as determined by isothermal titration calorimetry (ITC). BRD4 D1-IN-1 is primarily used in research related to cancer and inflammatory diseases, providing insights into the role of BRD4 in transcriptional regulation. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
