Product Data Sheet
dBAZ2
Catalog No. A40437
dBAZ2 is a novel PROTAC degrader targeting BAZ2A and BAZ2B, demonstrating DC50 values of 180 nM and 250 nM, respectively. This compound facilitates the ubiquitination and subsequent proteasomal degradation of BAZ2A and BAZ2B, making it a valuable tool for studying their biological roles. dBAZ2 is suitable for research applications in cancer biology, epigenetics, and the exploration of targeted protein degradation mechanisms.
Chemical Information
| Catalog Num | A40437 |
|---|---|
| M. Wt | 1030.29 |
| Formula | C54H64FN11O5S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3104449-57-9 |
| Synonyms | |
| SMILES | CC1=C(SC=N1)C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(SC[C@H]4CC[C@@H](CC4)COCC5=NC(C6=CN(N=C6)C)=C(N5CCC7=CN(N=C7)C)C8=CC=C(C=C8)C#N)C)NC(C9(CC9)F)=O)=O)O)=O |
Biological Activity
| Description | dBAZ2 is a novel PROTAC degrader targeting BAZ2A and BAZ2B, demonstrating DC50 values of 180 nM and 250 nM, respectively. This compound facilitates the ubiquitination and subsequent proteasomal degradation of BAZ2A and BAZ2B, making it a valuable tool for studying their biological roles. dBAZ2 is suitable for research applications in cancer biology, epigenetics, and the exploration of targeted protein degradation mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
