Product Data Sheet
PROTAC BRD4 Degrader-20
Catalog No. A40442
PROTAC BRD4 Degrader-20 is a bifunctional molecule designed to selectively degrade the bromodomain-containing protein 4 (BRD4). By harnessing the cellular ubiquitin-proteasome system, it effectively reduces BRD4 protein levels, leading to the modulation of transcriptional regulation associated with various diseases. This compound is primarily utilized in research applications targeting cancer and other pathologies where BRD4 plays a pivotal role in gene expression and cellular signaling.
Chemical Information
| Catalog Num | A40442 |
|---|---|
| M. Wt | 1056.69 |
| Formula | C55H58ClN9O7S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2086300-61-8 |
| Synonyms | |
| SMILES | CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(N[C@H]4C[C@H](C4)OC5=CC=C(OC(C(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(N[C@H](C7=CC=C(C8=C(N=CS8)C)C=C7)C)=O)=O)=O)=C9)C9=C5)=O)C%10=NN=C(C)N2%10 |
Biological Activity
| Description | PROTAC BRD4 Degrader-20 is a bifunctional molecule designed to selectively degrade the bromodomain-containing protein 4 (BRD4). By harnessing the cellular ubiquitin-proteasome system, it effectively reduces BRD4 protein levels, leading to the modulation of transcriptional regulation associated with various diseases. This compound is primarily utilized in research applications targeting cancer and other pathologies where BRD4 plays a pivotal role in gene expression and cellular signaling. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
