Product Data Sheet

UK 343664

Catalog No. A40443

main product photo
UK 343664 is a selective inhibitor of phosphodiesterase 5 (PDE5), demonstrating significant potency and oral bioavailability. This compound has been shown to partially reverse thromboxane-induced pulmonary hypertension, indicating its potential therapeutic applications in treating cardiovascular disorders associated with pulmonary hypertension.
Chemical Information
Catalog NumA40443
M. Wt565.69
FormulaC28H35N7O4S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.215297-27-1
Synonyms
SMILESO=C1N=C(C2=C(OCCC)C=CC(S(=O)(N3CCN(CC3)CC)=O)=C2)NC4=C(CC)N(CC5=NC=CC=C5)N=C41
Biological Activity
DescriptionUK 343664 is a selective inhibitor of phosphodiesterase 5 (PDE5), demonstrating significant potency and oral bioavailability. This compound has been shown to partially reverse thromboxane-induced pulmonary hypertension, indicating its potential therapeutic applications in treating cardiovascular disorders associated with pulmonary hypertension.
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