Product Data Sheet
Bi-magnolignan
Catalog No. A40451
Bi-magnolignan is an inhibitor of BRD4, a key regulator involved in the recognition of acetylated lysines on histones and non-histone proteins. This compound has been shown to induce DNA damage and promote apoptosis in cancer cells, specifically inhibiting the proliferation of HCT116 cells with an IC50 value of 2.9 μM. Bi-magnolignan may serve as a valuable tool for elucidating the role of BRD4 in cancer biology and for developing novel therapeutic strategies against BRD4-dependent malignancies.
Chemical Information
| Catalog Num | A40451 |
|---|---|
| M. Wt | 558.62 |
| Formula | C36H30O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2883117-61-9 |
| Synonyms | |
| SMILES | C=CCC1=C(O)C(O)=C(C2=C3C(OC4=C3C=C(CC=C)C=C4)=C(CC=C)C(O)=C2O)C5=C1OC6=CC=C(CC=C)C=C65 |
Biological Activity
| Description | Bi-magnolignan is an inhibitor of BRD4, a key regulator involved in the recognition of acetylated lysines on histones and non-histone proteins. This compound has been shown to induce DNA damage and promote apoptosis in cancer cells, specifically inhibiting the proliferation of HCT116 cells with an IC50 value of 2.9 μM. Bi-magnolignan may serve as a valuable tool for elucidating the role of BRD4 in cancer biology and for developing novel therapeutic strategies against BRD4-dependent malignancies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
