Product Data Sheet
BET-IN-15
Catalog No. A40478
BET-IN-15 is a potent bromodomain and extraterminal (BET) inhibitor that targets BRD4 with IC50 values of 0.64 nM and 0.25 nM for BRD4-BD1 and BRD4-BD2, respectively. This compound exhibits significant antiproliferative activity, making it an important tool for studying the role of BET proteins in cancer and other diseases. Researchers can utilize BET-IN-15 in investigations of transcriptional regulation and the therapeutic potential of BET inhibition in oncology.
Chemical Information
| Catalog Num | A40478 |
|---|---|
| M. Wt | 444.45 |
| Formula | C21H18F2N4O3S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2408994-22-7 |
| Synonyms | |
| SMILES | O=C1C2=C(C(C3=C(OC4=CC=C(C=C4F)F)C=CC(N=S(C)(C)=O)=N3)=CN1C)C=CN2 |
Biological Activity
| Description | BET-IN-15 is a potent bromodomain and extraterminal (BET) inhibitor that targets BRD4 with IC50 values of 0.64 nM and 0.25 nM for BRD4-BD1 and BRD4-BD2, respectively. This compound exhibits significant antiproliferative activity, making it an important tool for studying the role of BET proteins in cancer and other diseases. Researchers can utilize BET-IN-15 in investigations of transcriptional regulation and the therapeutic potential of BET inhibition in oncology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
