Product Data Sheet

SMARCA2-IN-1

Catalog No. A40496

main product photo
SMARCA2-IN-1 is a selective inhibitor of the SWI/SNF chromatin remodeling complex, specifically targeting SMARCA2. With an IC50 of greater than 1000 nM in H1299 cell lines, this compound is useful for studying the role of SMARCA2 in chromatin dynamics and epigenetic regulation. It has potential applications in cancer research, particularly in understanding the implications of chromatin remodeling in tumor progression and therapeutic resistance.
Chemical Information
Catalog NumA40496
M. Wt211.22
FormulaC12H9N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2568055-21-8
Synonyms
SMILESOC1=C(C2=CC(C=CN3)=C3N=N2)C=CC=C1
Biological Activity
DescriptionSMARCA2-IN-1 is a selective inhibitor of the SWI/SNF chromatin remodeling complex, specifically targeting SMARCA2. With an IC50 of greater than 1000 nM in H1299 cell lines, this compound is useful for studying the role of SMARCA2 in chromatin dynamics and epigenetic regulation. It has potential applications in cancer research, particularly in understanding the implications of chromatin remodeling in tumor progression and therapeutic resistance.
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SHIPPING AND STORAGE
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