Product Data Sheet

BRD4-IN-8

Catalog No. A40498

main product photo
BRD4-IN-8 is a selective inhibitor of the bromodomain-containing protein 4 (BRD4). It modulates gene expression by disrupting the interaction between BRD4 and acetylated histones, leading to the inhibition of transcriptional elongation. This compound has been shown to exhibit anti-cancer activity and is utilized in research investigating the therapeutic potential of targeting the BRD4 pathway in various malignancies.
Chemical Information
Catalog NumA40498
M. Wt387.43
FormulaC23H21N3O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1445992-82-4
Synonyms
SMILESCCNC(C1=CC(C2=CN(C)C(C3=C2C=CN3)=O)=C(OC4=CC=CC=C4)C=C1)=O
Biological Activity
DescriptionBRD4-IN-8 is a selective inhibitor of the bromodomain-containing protein 4 (BRD4). It modulates gene expression by disrupting the interaction between BRD4 and acetylated histones, leading to the inhibition of transcriptional elongation. This compound has been shown to exhibit anti-cancer activity and is utilized in research investigating the therapeutic potential of targeting the BRD4 pathway in various malignancies.
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