Product Data Sheet
BRD4 D1-IN-2
Catalog No. A40519
BRD4 D1-IN-2 is a selective inhibitor targeting BRD4 D1, exhibiting a potent IC50 of less than 0.092 µM. With an affinity of 15 nM for BRD4 D1, this compound demonstrates over 500-fold selectivity against both BRD2 D1 and BRD4 D2, as determined by isothermal titration calorimetry (ITC). BRD4 D1-IN-2 is valuable for research applications exploring the role of BRD4 in epigenetic regulation and its implications in cancer and other diseases.
Chemical Information
| Catalog Num | A40519 |
|---|---|
| M. Wt | 592.70 |
| Formula | C33H39F3N6O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2863687-22-1 |
| Synonyms | |
| SMILES | CC(C1=CC=C(C(OC2=NC(C3=C(N=CN3C4CCN(CC4)CCN(C)C)C5=CC=C(C=C5)C(F)(F)F)=CC=N2)=C1)C)C |
Biological Activity
| Description | BRD4 D1-IN-2 is a selective inhibitor targeting BRD4 D1, exhibiting a potent IC50 of less than 0.092 µM. With an affinity of 15 nM for BRD4 D1, this compound demonstrates over 500-fold selectivity against both BRD2 D1 and BRD4 D2, as determined by isothermal titration calorimetry (ITC). BRD4 D1-IN-2 is valuable for research applications exploring the role of BRD4 in epigenetic regulation and its implications in cancer and other diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
