Product Data Sheet

XL-126

Catalog No. A40534

main product photo
XL-126 is a selective inhibitor of the bromodomain and extraterminal (BET) protein family, specifically targeting BD1 with a Kd of 8.9 nM. This compound demonstrates significant anti-inflammatory properties while preserving platelet function, making it a valuable tool for research into inflammatory disorders and hematological conditions. XL-126 is particularly useful in studies aimed at understanding the role of BET proteins in disease pathways and therapeutics.
Chemical Information
Catalog NumA40534
M. Wt611.76
FormulaC33H37N7O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3033576-12-1
Synonyms
SMILESO=C1C(NC2CCNCC2)=CC(C3=CC(NS(=O)(CC)=O)=C(C4=C3)C=CN4C(C)(C5=NC=CC=C5)C6=CC=CC=N6)=CN1C
Biological Activity
DescriptionXL-126 is a selective inhibitor of the bromodomain and extraterminal (BET) protein family, specifically targeting BD1 with a Kd of 8.9 nM. This compound demonstrates significant anti-inflammatory properties while preserving platelet function, making it a valuable tool for research into inflammatory disorders and hematological conditions. XL-126 is particularly useful in studies aimed at understanding the role of BET proteins in disease pathways and therapeutics.
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