Product Data Sheet
dBRD9 dihydrochloride
Catalog No. A40535
dBRD9 dihydrochloride is a selective degrader of BRD9, targeting the protein for degradation through the PROTAC mechanism. This compound demonstrates efficacy in inhibiting the proliferation of acute myeloid leukemia (AML) cell lines, making it a valuable tool for research in cancer biology and therapeutic development. Its utility in studying BRD9's role in oncogenic processes positions dBRD9 dihydrochloride as a significant reagent for investigators exploring targeted protein degradation strategies.
Chemical Information
| Catalog Num | A40535 |
|---|---|
| M. Wt | 856.75 |
| Formula | C40H47Cl2N7O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2341840-98-8 |
| Synonyms | |
| SMILES | O=C(NCCOCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CN(CC4=C(OC)C=C(C(C5=CC=NC=C65)=CN(C)C6=O)C=C4OC)C.Cl.Cl |
Biological Activity
| Description | dBRD9 dihydrochloride is a selective degrader of BRD9, targeting the protein for degradation through the PROTAC mechanism. This compound demonstrates efficacy in inhibiting the proliferation of acute myeloid leukemia (AML) cell lines, making it a valuable tool for research in cancer biology and therapeutic development. Its utility in studying BRD9's role in oncogenic processes positions dBRD9 dihydrochloride as a significant reagent for investigators exploring targeted protein degradation strategies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
