Product Data Sheet

SMARCA2/4-IN-1

Catalog No. A40552

main product photo
SMARCA2/4-IN-1 is a selective inhibitor targeting SMARCA2 and SMARCA4, with reported IC50 values of 3.8 µM and 1.7 µM, respectively. This compound demonstrates significant inhibition of these chromatin remodeling factors, making it a valuable tool for studying epigenetic regulation and its impact on gene expression. It has potential applications in cancer research and therapeutic investigations aimed at manipulating chromatin dynamics.
Chemical Information
Catalog NumA40552
M. Wt248.67
FormulaC11H9ClN4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.76947-79-0
Synonyms
SMILESO=C(NC1=NC=CC=C1)NC2=CC(Cl)=NC=C2
Biological Activity
DescriptionSMARCA2/4-IN-1 is a selective inhibitor targeting SMARCA2 and SMARCA4, with reported IC50 values of 3.8 µM and 1.7 µM, respectively. This compound demonstrates significant inhibition of these chromatin remodeling factors, making it a valuable tool for studying epigenetic regulation and its impact on gene expression. It has potential applications in cancer research and therapeutic investigations aimed at manipulating chromatin dynamics.
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