Product Data Sheet
PBRM1-BD2-IN-4
Catalog No. A40556
PBRM1-BD2-IN-4 is a selective inhibitor of the PBRM1 bromodomain, exhibiting Kd values of 5.5 μM and 11.1 μM for PBRM1-BD2 and PBRM1-BD5, respectively, with an IC50 of 0.2 μM for PBRM1-BD2. This compound is instrumental in studying the role of PBRM1 in cancer biology and may contribute to the development of anticancer therapies targeting bromodomain-containing proteins. Its high potency and specificity make it a valuable tool for research focused on epigenetic regulation in cancer contexts.
Chemical Information
| Catalog Num | A40556 |
|---|---|
| M. Wt | 272.73 |
| Formula | C15H13ClN2O |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2819989-60-9 |
| Synonyms | |
| SMILES | O=C1NC(C2=CC=CC=C2C)NC3=C1C(Cl)=CC=C3 |
Biological Activity
| Description | PBRM1-BD2-IN-4 is a selective inhibitor of the PBRM1 bromodomain, exhibiting Kd values of 5.5 μM and 11.1 μM for PBRM1-BD2 and PBRM1-BD5, respectively, with an IC50 of 0.2 μM for PBRM1-BD2. This compound is instrumental in studying the role of PBRM1 in cancer biology and may contribute to the development of anticancer therapies targeting bromodomain-containing proteins. Its high potency and specificity make it a valuable tool for research focused on epigenetic regulation in cancer contexts. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
