Product Data Sheet
BiBET
Catalog No. A40609
BiBET is a bivalent chemical probe targeting the BET family of bromodomain-containing proteins, specifically BRD4. It exhibits the ability to simultaneously bind to two bromodomains through a cis-binding mechanism. This unique interaction profile makes BiBET valuable for studying the role of BET proteins in cellular processes, particularly in cancer biology and inflammatory responses. Researchers can utilize BiBET to investigate the regulatory mechanisms of gene expression mediated by BRD4 and explore potential therapeutic strategies against related diseases.
Chemical Information
| Catalog Num | A40609 |
|---|---|
| M. Wt | 530.58 |
| Formula | C26H30N10O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2059110-46-0 |
| Synonyms | |
| SMILES | CN(CCOC1=CC=C(C2CCN(C3=NN4C(C=C3)=NN=C4OC)CC2)C=C1)C5=NN6C(C=C5)=NN=C6OC |
Biological Activity
| Description | BiBET is a bivalent chemical probe targeting the BET family of bromodomain-containing proteins, specifically BRD4. It exhibits the ability to simultaneously bind to two bromodomains through a cis-binding mechanism. This unique interaction profile makes BiBET valuable for studying the role of BET proteins in cellular processes, particularly in cancer biology and inflammatory responses. Researchers can utilize BiBET to investigate the regulatory mechanisms of gene expression mediated by BRD4 and explore potential therapeutic strategies against related diseases. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
