Product Data Sheet
JNK3 inhibitor-7
Catalog No. A40662
JNK3 Inhibitor-7 is a selective inhibitor of the c-Jun N-terminal kinase 3 (JNK3) pathway, exhibiting potent activity with IC50 values of 53 nM for JNK3, while demonstrating lesser inhibition against JNK2 and JNK1 at 973 nM and 1039 nM, respectively. This compound effectively crosses the blood-brain barrier and exhibits significant neuroprotective properties. JNK3 Inhibitor-7 holds potential for research applications related to neurodegenerative disorders, particularly Alzheimer's disease.
Chemical Information
| Catalog Num | A40662 |
|---|---|
| M. Wt | 561.63 |
| Formula | C32H31N7O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3034676-52-0 |
| Synonyms | |
| SMILES | CNC(OC1=CC=C2N=C(C3=CC4=C(C=CC=C4)C=C3)N(C5=NC(N[C@@H]6CN(CCC6)C(C7CC7)=O)=NC=C5)C2=C1)=O |
Biological Activity
| Description | JNK3 Inhibitor-7 is a selective inhibitor of the c-Jun N-terminal kinase 3 (JNK3) pathway, exhibiting potent activity with IC50 values of 53 nM for JNK3, while demonstrating lesser inhibition against JNK2 and JNK1 at 973 nM and 1039 nM, respectively. This compound effectively crosses the blood-brain barrier and exhibits significant neuroprotective properties. JNK3 Inhibitor-7 holds potential for research applications related to neurodegenerative disorders, particularly Alzheimer's disease. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
