Product Data Sheet

JNK3 inhibitor-8

Catalog No. A40669

main product photo
JNK3 Inhibitor-8 is a selective, orally bioavailable inhibitor targeting the c-Jun N-terminal kinase 3 (JNK3) with an IC50 of 21 nM. It demonstrates pronounced neuroprotective effects and effectively crosses the blood-brain barrier. This compound is relevant for research applications related to neurodegenerative disorders, particularly Alzheimer’s disease.
Chemical Information
Catalog NumA40669
M. Wt579.62
FormulaC32H30FN7O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3034676-53-1
Synonyms
SMILESO=C(N1C[C@@H](NC2=NC=CC(N3C4=C(N=C3C5=CC6=C(C=C5)C=CC=C6)C(F)=CC(OC(NC)=O)=C4)=N2)CCC1)C7CC7
Biological Activity
DescriptionJNK3 Inhibitor-8 is a selective, orally bioavailable inhibitor targeting the c-Jun N-terminal kinase 3 (JNK3) with an IC50 of 21 nM. It demonstrates pronounced neuroprotective effects and effectively crosses the blood-brain barrier. This compound is relevant for research applications related to neurodegenerative disorders, particularly Alzheimer’s disease.
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SHIPPING AND STORAGE
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