Product Data Sheet
JNK3 inhibitor-2
Catalog No. A40676
JNK3 Inhibitor-2 is a selective inhibitor targeting c-Jun N-terminal kinase 3 (JNK3), demonstrating an IC50 of 0.25 µM for JNK3, with minimal activity against JNK1 and JNK2 (>100 µM). This compound exhibits additional inhibitory effects on DDR1 and EGFR variants (T790M, L858R). JNK3 Inhibitor-2 is valuable for research applications focusing on cellular stress response and cancer signaling pathways, particularly in studies investigating JNK3’s role in neurodegeneration and oncogenesis.
Chemical Information
| Catalog Num | A40676 |
|---|---|
| M. Wt | 314.34 |
| Formula | C20H14N2O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2366264-18-6 |
| Synonyms | |
| SMILES | O=C1NC2=C(C=CC=C2)N/C1=C\C(C3=C4C=CC=CC4=CC=C3)=O |
Biological Activity
| Description | JNK3 Inhibitor-2 is a selective inhibitor targeting c-Jun N-terminal kinase 3 (JNK3), demonstrating an IC50 of 0.25 µM for JNK3, with minimal activity against JNK1 and JNK2 (>100 µM). This compound exhibits additional inhibitory effects on DDR1 and EGFR variants (T790M, L858R). JNK3 Inhibitor-2 is valuable for research applications focusing on cellular stress response and cancer signaling pathways, particularly in studies investigating JNK3’s role in neurodegeneration and oncogenesis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
