Product Data Sheet
BRAF V600E/CRAF-IN-2
Catalog No. A40723
BRAF V600E/CRAF-IN-2 is a potent inhibitor targeting BRAF V600E and CRAF, demonstrating IC50 values of 0.888 μM and 0.229 μM, respectively. This compound induces apoptosis and effectively causes cell cycle arrest at the G0/G1 phase in HCT-116 colon cancer cells. BRAF V600E/CRAF-IN-2 is suitable for research applications focused on cancer biology and treatment strategies.
Chemical Information
| Catalog Num | A40723 |
|---|---|
| M. Wt | 549.59 |
| Formula | C30H30F3N5O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2499499-62-4 |
| Synonyms | |
| SMILES | CCN1CCN(CC1)C2=CC(C(F)(F)F)=CC(C(NC3=CC=CC(NC4=NC5=CC=CC(OC)=C5C=C4)=C3)=O)=C2 |
Biological Activity
| Description | BRAF V600E/CRAF-IN-2 is a potent inhibitor targeting BRAF V600E and CRAF, demonstrating IC50 values of 0.888 μM and 0.229 μM, respectively. This compound induces apoptosis and effectively causes cell cycle arrest at the G0/G1 phase in HCT-116 colon cancer cells. BRAF V600E/CRAF-IN-2 is suitable for research applications focused on cancer biology and treatment strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
