Product Data Sheet
p38 MAPK-IN-10
Catalog No. A40822
p38 MAPK-IN-10 is a potent inhibitor of p38 MAP kinase, exhibiting an IC50 of 570 nM. This orally active compound shows promise in the study of chronic inflammatory diseases, including rheumatoid arthritis and Crohn’s disease. Its mechanism of action targets the p38 MAPK signaling pathway, making it a valuable tool for researchers investigating therapeutic approaches to modulate inflammation.
Chemical Information
| Catalog Num | A40822 |
|---|---|
| M. Wt | 305.31 |
| Formula | C17H12FN5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 340041-97-6 |
| Synonyms | |
| SMILES | FC1=CC=C(C2=C(C3=CC=NC=C3)N4C=CC(N)=NC4=N2)C=C1 |
Biological Activity
| Description | p38 MAPK-IN-10 is a potent inhibitor of p38 MAP kinase, exhibiting an IC50 of 570 nM. This orally active compound shows promise in the study of chronic inflammatory diseases, including rheumatoid arthritis and Crohn’s disease. Its mechanism of action targets the p38 MAPK signaling pathway, making it a valuable tool for researchers investigating therapeutic approaches to modulate inflammation. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
