Product Data Sheet
PD-254552
Catalog No. A40858
PD-254552 is a potent inhibitor of MEK (mitogen-activated protein kinase/extracellular signal-regulated kinase kinase), playing a significant role in disrupting MAPK signaling pathways. This compound has demonstrated significant hepatotoxicity and gastrointestinal toxicity in murine models, providing valuable insights for researchers studying the side effects associated with MEK inhibition. Its properties make it a relevant candidate for investigations into cancer therapies and related pharmacological studies.
Chemical Information
| Catalog Num | A40858 |
|---|---|
| M. Wt | 480.27 |
| Formula | C19H18FIN4O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 284030-47-3 |
| Synonyms | |
| SMILES | O=C(NOCC1CC1)C2=C(C(F)=C3C(N=CN3)=C2)NC4=CC=C(C=C4C)I |
Biological Activity
| Description | PD-254552 is a potent inhibitor of MEK (mitogen-activated protein kinase/extracellular signal-regulated kinase kinase), playing a significant role in disrupting MAPK signaling pathways. This compound has demonstrated significant hepatotoxicity and gastrointestinal toxicity in murine models, providing valuable insights for researchers studying the side effects associated with MEK inhibition. Its properties make it a relevant candidate for investigations into cancer therapies and related pharmacological studies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
