Product Data Sheet
MYX1715
Catalog No. A40995
MYX1715 is a potent inhibitor of N-Myristoyltransferase (NMT) with a KD value of 0.09 nM. This compound effectively inhibits the proliferation of LU0884 and LU2511 cell lines, demonstrating IC50 values of 44 nM and 9 nM, respectively. MYX1715 has shown significant antitumor activity against neuroblastoma and gastric cancer in murine models, and it may be exploited as an antibody-drug conjugate (ADC) toxin for targeted cancer therapies.
Chemical Information
| Catalog Num | A40995 |
|---|---|
| M. Wt | 480.99 |
| Formula | C25H29ClN6O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2445448-66-6 |
| Synonyms | IMP1320 |
| SMILES | O=C(N(C)C)C1=NN(C)C(C)=C1CCOC2=C(C3=CN4C(CCN)=CN=C4C=C3)C=CC(Cl)=C2 |
Biological Activity
| Description | MYX1715 is a potent inhibitor of N-Myristoyltransferase (NMT) with a KD value of 0.09 nM. This compound effectively inhibits the proliferation of LU0884 and LU2511 cell lines, demonstrating IC50 values of 44 nM and 9 nM, respectively. MYX1715 has shown significant antitumor activity against neuroblastoma and gastric cancer in murine models, and it may be exploited as an antibody-drug conjugate (ADC) toxin for targeted cancer therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
