Product Data Sheet
SC209
Catalog No. A41017
SC209, a 3-aminophenyl hemiasterlin derivative, targets tubulin as an ADC cytotoxin. This compound demonstrates reduced efflux potential through the P-glycoprotein 1 pump when compared to other tubulin-targeting agents, enhancing its efficacy in therapeutic applications. SC209 exhibits significant antitumor activity and is suitable for the synthesis of antibody-drug conjugates (ADCs), making it a valuable reagent in cancer research.
Chemical Information
| Catalog Num | A41017 |
|---|---|
| M. Wt | 488.66 |
| Formula | C27H44N4O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1977557-86-0 |
| Synonyms | 3-Aminophenyl Hemiasterlin |
| SMILES | OC(/C(C)=C/[C@H](C(C)C)N(C)C([C@H](C(C)(C)C)NC([C@@H](NC)C(C)(C1=CC(N)=CC=C1)C)=O)=O)=O |
Biological Activity
| Description | SC209, a 3-aminophenyl hemiasterlin derivative, targets tubulin as an ADC cytotoxin. This compound demonstrates reduced efflux potential through the P-glycoprotein 1 pump when compared to other tubulin-targeting agents, enhancing its efficacy in therapeutic applications. SC209 exhibits significant antitumor activity and is suitable for the synthesis of antibody-drug conjugates (ADCs), making it a valuable reagent in cancer research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
