Product Data Sheet
DMEA-PNU-159682
Catalog No. A41074
DMEA-PNU-159682 is an antibody-drug conjugate (ADC) cytotoxin that combines the metabolites of nemorubicin (MMDX) with the potent cytotoxic agent PNU-159682. This compound exhibits significant cytotoxicity, making it a valuable tool for targeted cancer therapies. Its unique mechanism of action allows for selective delivery of cytotoxic agents to tumor cells, thereby enhancing therapeutic efficacy while minimizing off-target effects in research applications focused on ADC development and optimization.
Chemical Information
| Catalog Num | A41074 |
|---|---|
| M. Wt | 755.76 |
| Formula | C37H45N3O14 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1799421-48-9 |
| Synonyms | |
| SMILES | C[C@H]1[C@]2([H])[C@](N3[C@]([C@H](OCC3)OC)([H])O2)([H])C[C@](O1)([H])O[C@@H]4C5=C(C[C@](C(COC(N(C)CCNC)=O)=O)(O)C4)C(O)=C6C(C(C7=C(OC)C=CC=C7C6=O)=O)=C5O |
Biological Activity
| Description | DMEA-PNU-159682 is an antibody-drug conjugate (ADC) cytotoxin that combines the metabolites of nemorubicin (MMDX) with the potent cytotoxic agent PNU-159682. This compound exhibits significant cytotoxicity, making it a valuable tool for targeted cancer therapies. Its unique mechanism of action allows for selective delivery of cytotoxic agents to tumor cells, thereby enhancing therapeutic efficacy while minimizing off-target effects in research applications focused on ADC development and optimization. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
