Product Data Sheet
Dimethyl-SGD-1882
Catalog No. A41116
Dimethyl-SGD-1882 is a highly potent DNA alkylator, specifically designed for use as an antibody-drug conjugate (ADC) cytotoxin. It acts by forming covalent bonds with DNA, leading to the inhibition of DNA replication and subsequent induction of cytotoxicity in rapidly dividing cancer cells. This compound is valuable for research applications focused on targeted cancer therapies and the development of novel ADCs.
Chemical Information
| Catalog Num | A41116 |
|---|---|
| M. Wt | 753.84 |
| Formula | C44H43N5O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3026416-27-0 |
| Synonyms | Dimethyl-PBD dimer |
| SMILES | C[C@@]12N(C(C3=CC(OC)=C(OCCCOC4=C(C=C5C(N=C[C@]6(C)N(C=C(C7=CC=C(OC)C=C7)C6)C5=O)=C4)OC)C=C3N=C2)=O)C=C(C8=CC=C(N)C=C8)C1 |
Biological Activity
| Description | Dimethyl-SGD-1882 is a highly potent DNA alkylator, specifically designed for use as an antibody-drug conjugate (ADC) cytotoxin. It acts by forming covalent bonds with DNA, leading to the inhibition of DNA replication and subsequent induction of cytotoxicity in rapidly dividing cancer cells. This compound is valuable for research applications focused on targeted cancer therapies and the development of novel ADCs. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
