Product Data Sheet
Dorzolamide-d5(hydrochloride)
Catalog No. A41206
Dorzolamide-d5 (hydrochloride) is a deuterated form of Dorzolamide (hydrochloride), a potent inhibitor of carbonic anhydrase II. This compound exhibits exceptional inhibitory activity, with IC50 values of 0.18 nM for red blood cell carbonic anhydrase II and 600 nM for carbonic anhydrase I. Dorzolamide is also recognized for its anti-tumor properties, making it a valuable reagent for research in cancer biology and enzyme inhibition studies.
Chemical Information
| Catalog Num | A41206 |
|---|---|
| M. Wt | 365.93 |
| Formula | C10H12D5ClN2O4S3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2749856-75-3 |
| Synonyms | L671152 hydrochloride-d5; MK507 hydrochlorid-d5 |
| SMILES | O=S1([C@H](C[C@@H](C2=C1SC(S(N)(=O)=O)=C2)NC([2H])(C([2H])([2H])[2H])[2H])C)=O.Cl |
Biological Activity
| Description | Dorzolamide-d5 (hydrochloride) is a deuterated form of Dorzolamide (hydrochloride), a potent inhibitor of carbonic anhydrase II. This compound exhibits exceptional inhibitory activity, with IC50 values of 0.18 nM for red blood cell carbonic anhydrase II and 600 nM for carbonic anhydrase I. Dorzolamide is also recognized for its anti-tumor properties, making it a valuable reagent for research in cancer biology and enzyme inhibition studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
