Product Data Sheet

Methazolamide-d6

Catalog No. A41264

main product photo
Methazolamide-d6 is the deuterated form of Methazolamide, a sulfonamide derivative that functions as a potent inhibitor of carbonic anhydrase II, exhibiting a Ki value of 14 nM. This compound is primarily utilized in research focused on ocular conditions, particularly for its ability to lower intraocular pressure in models of glaucoma and other related disorders. Methazolamide-d6 serves as a valuable tool for studying carbonic anhydrase activity and exploring pharmacokinetic properties through stable isotope labeling.
Chemical Information
Catalog NumA41264
M. Wt242.31
FormulaC5H2D6N4O3S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1795142-30-1
SynonymsL584601-d6
SMILES[2H]C([2H])([2H])C(/N=C1SC(S(N)(=O)=O)=NN\1C([2H])([2H])[2H])=O
Biological Activity
DescriptionMethazolamide-d6 is the deuterated form of Methazolamide, a sulfonamide derivative that functions as a potent inhibitor of carbonic anhydrase II, exhibiting a Ki value of 14 nM. This compound is primarily utilized in research focused on ocular conditions, particularly for its ability to lower intraocular pressure in models of glaucoma and other related disorders. Methazolamide-d6 serves as a valuable tool for studying carbonic anhydrase activity and exploring pharmacokinetic properties through stable isotope labeling.
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