Product Data Sheet
CAI0019
Catalog No. A41280
CAI0019 is an orally active inhibitor of α-carbonic anhydrase, designed based on the Acetazolamide framework. It demonstrates narrow-spectrum antibiofilm activity, with a MIC50 of 0.094 μM and a MIC90 of 0.39 μM. In a septic peritonitis mouse model, CAI0019 selectively inhibits Enterococcus while sparing most intestinal commensal bacteria, making it a valuable tool for research into antimicrobial therapies and biofilm-associated infections.
Chemical Information
| Catalog Num | A41280 |
|---|---|
| M. Wt | 318.42 |
| Formula | C11H18N4O3S2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2446169-48-6 |
| Synonyms | |
| SMILES | O=C(CCC1CCCCC1)NC2=NN=C(S2)S(=O)(N)=O |
Biological Activity
| Description | CAI0019 is an orally active inhibitor of α-carbonic anhydrase, designed based on the Acetazolamide framework. It demonstrates narrow-spectrum antibiofilm activity, with a MIC50 of 0.094 μM and a MIC90 of 0.39 μM. In a septic peritonitis mouse model, CAI0019 selectively inhibits Enterococcus while sparing most intestinal commensal bacteria, making it a valuable tool for research into antimicrobial therapies and biofilm-associated infections. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
