Product Data Sheet
Dorzolamide-d5
Catalog No. A41301
Dorzolamide-d5 is a deuterated form of Dorzolamide, a potent inhibitor of carbonic anhydrase II, demonstrating IC50 values of 0.18 nM for red blood cell CA-II and 600 nM for CA-I. This stable isotope variant serves as a valuable tool for tracing and analyzing metabolic pathways involving carbonic anhydrases. Additionally, Dorzolamide's anti-tumor activity makes it relevant for cancer research applications, providing insights into its molecular mechanisms.
Chemical Information
| Catalog Num | A41301 |
|---|---|
| M. Wt | 329.47 |
| Formula | C10H11D5N2O4S3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1227097-70-2 |
| Synonyms | |
| SMILES | O=S1(=O)C2=C([C@@H](NC(C([2H])([2H])[2H])([2H])[2H])C[C@@H]1C)C=C(S(N)(=O)=O)S2 |
Biological Activity
| Description | Dorzolamide-d5 is a deuterated form of Dorzolamide, a potent inhibitor of carbonic anhydrase II, demonstrating IC50 values of 0.18 nM for red blood cell CA-II and 600 nM for CA-I. This stable isotope variant serves as a valuable tool for tracing and analyzing metabolic pathways involving carbonic anhydrases. Additionally, Dorzolamide's anti-tumor activity makes it relevant for cancer research applications, providing insights into its molecular mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
