Dealanylascamycin
Catalog No. A41302

Dealanylascamycin is a nucleoside antibiotic that functions as a carbonic anhydrase (CA) inhibitor, exhibiting Ki values of 167, 65.2, 234, and 143 nM for human CA isoforms I, II, IV, and IX, respectively. This compound demonstrates broad-spectrum antibacterial activity, notably effective against pathogens such as Xanthomonas citri with a minimum inhibitory concentration (MIC) of 0.4 μg/mL. Additionally, Dealanylascamycin displays significant cytotoxicity, making it a substance of interest for various biological research applications, particularly in the study of antimicrobial effects and CA inhibition.
Chemical Information
| Catalog Num | A41302 |
|---|---|
| M. Wt | 380.76 |
| Formula | C10H13ClN6O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 66522-52-9 |
| Synonyms | AT-265 |
| SMILES | O[C@H]1[C@@H](O)[C@H](N2C3=NC(Cl)=NC(N)=C3N=C2)O[C@@H]1COS(N)(=O)=O |
Biological Activity
| Description | Dealanylascamycin is a nucleoside antibiotic that functions as a carbonic anhydrase (CA) inhibitor, exhibiting Ki values of 167, 65.2, 234, and 143 nM for human CA isoforms I, II, IV, and IX, respectively. This compound demonstrates broad-spectrum antibacterial activity, notably effective against pathogens such as Xanthomonas citri with a minimum inhibitory concentration (MIC) of 0.4 μg/mL. Additionally, Dealanylascamycin displays significant cytotoxicity, making it a substance of interest for various biological research applications, particularly in the study of antimicrobial effects and CA inhibition. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


