Product Data Sheet
AZ14170133
Catalog No. A41325
AZ14170133 is a drug-linker conjugate specifically designed for antibody-drug conjugates (ADCs). This compound comprises a cytotoxic payload, a topoisomerase 1 inhibitor, linked for effective targeted delivery. AZ14170133 is utilized in the synthesis of ADCs such as AZD9592 and AZD8205, making it a valuable tool for cancer research focused on developing innovative therapeutic strategies.
Chemical Information
| Catalog Num | A41325 |
|---|---|
| M. Wt | 1148.26 |
| Formula | C57H77N7O18 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2495742-34-0 |
| Synonyms | SG 3932; AZ-0133 |
| SMILES | O=C1N2C(C(C(C2)=C3C4=C5CCC3)=NC4=CC=C5NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN6C(C=CC6=O)=O)=O)=O)=O)=O)=CC7=C1COC([C@]7(O)CC)=O |
Biological Activity
| Description | AZ14170133 is a drug-linker conjugate specifically designed for antibody-drug conjugates (ADCs). This compound comprises a cytotoxic payload, a topoisomerase 1 inhibitor, linked for effective targeted delivery. AZ14170133 is utilized in the synthesis of ADCs such as AZD9592 and AZD8205, making it a valuable tool for cancer research focused on developing innovative therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
