Product Data Sheet
Gly3-VC-PAB-MMAE
Catalog No. A41326
Gly3-VC-PAB-MMAE is a cleavable drug-linker conjugate comprising the linker Gly3-VC-PAB and the potent tubulin inhibitor MMAE. This compound facilitates the synthesis of antibody-drug conjugates (ADCs) by enabling targeted delivery of MMAE to cancer cells. Its unique structure allows for the selective release of the cytotoxic agent in the tumor microenvironment, making it valuable in cancer research and therapeutic development.
Chemical Information
| Catalog Num | A41326 |
|---|---|
| M. Wt | 1294.58 |
| Formula | C64H103N13O15 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2684216-48-4 |
| Synonyms | |
| SMILES | CC[C@@H]([C@H](N(C)C([C@@H](NC([C@@H](N(C)C(OCC1=CC=C(C=C1)NC([C@@H](NC([C@@H](NC(CNC(CNC(CN)=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)=O)C(C)C)=O)C(C)C)=O)[C@H](OC)CC(N2[C@H]([C@H](OC)[C@H](C(N[C@@H]([C@H](C3=CC=CC=C3)O)C)=O)C)CCC2)=O)C |
Biological Activity
| Description | Gly3-VC-PAB-MMAE is a cleavable drug-linker conjugate comprising the linker Gly3-VC-PAB and the potent tubulin inhibitor MMAE. This compound facilitates the synthesis of antibody-drug conjugates (ADCs) by enabling targeted delivery of MMAE to cancer cells. Its unique structure allows for the selective release of the cytotoxic agent in the tumor microenvironment, making it valuable in cancer research and therapeutic development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
