Product Data Sheet

Mal-VC-PAB-DM1

Catalog No. A41327

main product photo
Mal-VC-PAB-DM1 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound features DM1, a potent microtubule-disrupting agent, linked by the Mal-VC-PAB linker, which enhances targeted delivery to tumor cells. Mal-VC-PAB-DM1 exhibits significant antitumor activity, making it a valuable tool for cancer research and therapeutic development.
Chemical Information
Catalog NumA41327
M. Wt1248.81
FormulaC61H82ClN9O17
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1464051-44-2
Synonyms
SMILESC[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)C=C5)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
Biological Activity
DescriptionMal-VC-PAB-DM1 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound features DM1, a potent microtubule-disrupting agent, linked by the Mal-VC-PAB linker, which enhances targeted delivery to tumor cells. Mal-VC-PAB-DM1 exhibits significant antitumor activity, making it a valuable tool for cancer research and therapeutic development.
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SHIPPING AND STORAGE
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