Product Data Sheet

Mal-PEG4-VC-PAB-DMEA-PNU-159682

Catalog No. A41338

main product photo
Mal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound combines the ADC linker Mal-PEG4-VC-PAB with the cytotoxic agent DMEA-PNU-159682, which derives from metabolites of nemorubicin (MMDX) processed by liver microsomes. It exhibits strong cytotoxicity, making it suitable for targeted cancer therapies in research focused on ADC development and optimization.
Chemical Information
Catalog NumA41338
M. Wt1559.62
FormulaC74H98N10O27
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2259318-52-8
Synonyms
SMILESC[C@H]1[C@]2([H])[C@](N3[C@]([C@H](OCC3)OC)([H])O2)([H])C[C@](O1)([H])O[C@@H]4C5=C(C[C@](C(COC(N(C)CCN(C)C(OCC6=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCN7C(C=CC7=O)=O)=O)=O)=O)=O)C=C6)=O)=O)=O)(O)C4)C(O)=C8C(C(C9=C(OC)C=CC=C9C8=O)=O)=C5O
Biological Activity
DescriptionMal-PEG4-VC-PAB-DMEA-PNU-159682 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound combines the ADC linker Mal-PEG4-VC-PAB with the cytotoxic agent DMEA-PNU-159682, which derives from metabolites of nemorubicin (MMDX) processed by liver microsomes. It exhibits strong cytotoxicity, making it suitable for targeted cancer therapies in research focused on ADC development and optimization.
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SHIPPING AND STORAGE
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