Product Data Sheet
endo-BCN-PEG4-Val-Cit-PAB-MMAE
Catalog No. A41352
endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable linker specifically designed for antibody-drug conjugates (ADCs), facilitating the targeted delivery of therapeutic agents. This compound features a 4-unit polyethylene glycol (PEG) chain and incorporates a BCN group that enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its versatility is highly applicable in the development of ADCs, enhancing the efficacy and specificity of cancer therapies.
Chemical Information
| Catalog Num | A41352 |
|---|---|
| M. Wt | 1546.93 |
| Formula | C80H127N11O19 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2762519-08-2 |
| Synonyms | |
| SMILES | CC[C@@H]([C@H](N(C([C@@H](NC([C@@H](N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCNC(OC[C@@H]2[C@@]3([H])[C@]2([H])CCC#CCC3)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C1)=O)C)C(C)C)=O)C(C)C)=O)C)[C@H](OC)CC(N4CCC[C@H]4[C@H](OC)[C@H](C(N[C@@H]([C@@H](O)C5=CC=CC=C5)C)=O)C)=O)C |
Biological Activity
| Description | endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable linker specifically designed for antibody-drug conjugates (ADCs), facilitating the targeted delivery of therapeutic agents. This compound features a 4-unit polyethylene glycol (PEG) chain and incorporates a BCN group that enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its versatility is highly applicable in the development of ADCs, enhancing the efficacy and specificity of cancer therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
