Product Data Sheet
DM21
Catalog No. A41356
DM21 is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). It features a maytansinoid microtubule-disrupting payload linked through a stable tripeptide linker, enhancing its therapeutic efficacy. DM21 is conjugated with a humanized antibody targeting ADAM9, resulting in the formulation of IMGC936, which holds promise in cancer research and targeted therapies.
Chemical Information
| Catalog Num | A41356 |
|---|---|
| M. Wt | 1215.84 |
| Formula | C58H83ClN8O16S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2243689-80-5 |
| Synonyms | |
| SMILES | C[C@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C(CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CCCCCSCNC([C@H](C)NC([C@@H](C)NC([C@H](C)NC(CCCCCN5C(C=CC5=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=C(C(OC)=C4)Cl)\C)OC)(NC(O3)=O)O)C)([H])O1 |
Biological Activity
| Description | DM21 is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). It features a maytansinoid microtubule-disrupting payload linked through a stable tripeptide linker, enhancing its therapeutic efficacy. DM21 is conjugated with a humanized antibody targeting ADAM9, resulting in the formulation of IMGC936, which holds promise in cancer research and targeted therapies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
