Product Data Sheet

Mal-PEG4-VA-PBD

Catalog No. A41357

main product photo
Mal-PEG4-VA-PBD is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It utilizes the potent antitumor antibiotic Pyrrolobenzodiazepine (PBD), which is covalently linked through Mal-PEG4-VA. This compound facilitates targeted delivery of PBD to tumor cells, enhancing therapeutic efficacy while minimizing off-target effects. Mal-PEG4-VA-PBD is ideal for research into ADC development and optimization in cancer therapy.
Chemical Information
Catalog NumA41357
M. Wt1294.40
FormulaC68H79N9O17
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1342820-68-1
Synonyms
SMILES[H][C@]12N(C(C3=CC(OC)=C(OCCCOC4=C(C=C5C(N=C[C@@]6([H])N(C=C(C7=CC=C(OC)C=C7)C6)C5=O)=C4)OC)C=C3N=C2)=O)C=C(C8=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCN9C(C=CC9=O)=O)=O)=O)=O)=O)C=C8)C1
Biological Activity
DescriptionMal-PEG4-VA-PBD is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It utilizes the potent antitumor antibiotic Pyrrolobenzodiazepine (PBD), which is covalently linked through Mal-PEG4-VA. This compound facilitates targeted delivery of PBD to tumor cells, enhancing therapeutic efficacy while minimizing off-target effects. Mal-PEG4-VA-PBD is ideal for research into ADC development and optimization in cancer therapy.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.