Product Data Sheet
DBCO-Val-Cit-PAB-MMAE
Catalog No. A41362
DBCO-Val-Cit-PAB-MMAE is an ADC drug-linker conjugate designed for the synthesis of antibody-drug conjugates (ADCs). It incorporates the tubulin inhibitor MMAE, which acts as a cytotoxic agent targeting rapidly dividing cells. The DBCO-Val-Cit-PAB linker features an electrophilic group, facilitating stable conjugation to antibodies and enhancing the therapeutic efficacy of ADCs in cancer research applications.
Chemical Information
| Catalog Num | A41362 |
|---|---|
| M. Wt | 1410.74 |
| Formula | C77H107N11O14 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2768446-73-5 |
| Synonyms | |
| SMILES | O=C(N1[C@](CCC1)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCC(N4C5=CC=CC=C5C#CC6=CC=CC=C6C4)=O)=O)=O)=O)=O)=O)=O |
Biological Activity
| Description | DBCO-Val-Cit-PAB-MMAE is an ADC drug-linker conjugate designed for the synthesis of antibody-drug conjugates (ADCs). It incorporates the tubulin inhibitor MMAE, which acts as a cytotoxic agent targeting rapidly dividing cells. The DBCO-Val-Cit-PAB linker features an electrophilic group, facilitating stable conjugation to antibodies and enhancing the therapeutic efficacy of ADCs in cancer research applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
