Product Data Sheet
Gly-Gly-Phe-Gly-NH-O-CO-Exatecan
Catalog No. A41388
Gly-Gly-Phe-Gly-NH-O-CO-Exatecan is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, comprising a linker moiety and Exatecan, a potent topoisomerase I inhibitor. This compound facilitates the synthesis of ADC molecules, enabling targeted delivery of cytotoxic agents to tumor cells while minimizing off-target effects. Its unique structure allows for effective internalization and release of the active drug in the cellular environment, making it valuable for studies in cancer therapeutics and drug development.
Chemical Information
| Catalog Num | A41388 |
|---|---|
| M. Wt | 840.85 |
| Formula | C42H45FN8O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1599440-12-6 |
| Synonyms | |
| SMILES | CC1=C(F)C=C2C3=C1CC[C@H](NC(COCNC(CNC([C@H](CC4=CC=CC=C4)NC(CNC(CN)=O)=O)=O)=O)=O)C3=C5C(C(N6C5)=CC([C@@](O)(CC)C(OC7)=O)=C7C6=O)=N2 |
Biological Activity
| Description | Gly-Gly-Phe-Gly-NH-O-CO-Exatecan is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, comprising a linker moiety and Exatecan, a potent topoisomerase I inhibitor. This compound facilitates the synthesis of ADC molecules, enabling targeted delivery of cytotoxic agents to tumor cells while minimizing off-target effects. Its unique structure allows for effective internalization and release of the active drug in the cellular environment, making it valuable for studies in cancer therapeutics and drug development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
