Product Data Sheet
APL-1081
Catalog No. A41405
APL-1081 is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). It features the Mal-Exo-EEVC peptide linker that facilitates effective targeting and delivery, combined with the potent tubulin polymerization inhibitor MMAE. This compound demonstrates significant biological activity by disrupting microtubule dynamics, making it valuable for research focused on cancer therapeutics and ADC development.
Chemical Information
| Catalog Num | A41405 |
|---|---|
| M. Wt | 1502.79 |
| Formula | C75H115N13O19 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2921735-80-8 |
| Synonyms | Mal-Exo-EVC-MMAE |
| SMILES | O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OC(C3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CCC(O)=O)=O)=O)=O)C(NCCCCCN4C(C=CC4=O)=O)=O)=O)=O)=O)=O)OC)=O |
Biological Activity
| Description | APL-1081 is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). It features the Mal-Exo-EEVC peptide linker that facilitates effective targeting and delivery, combined with the potent tubulin polymerization inhibitor MMAE. This compound demonstrates significant biological activity by disrupting microtubule dynamics, making it valuable for research focused on cancer therapeutics and ADC development. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
