Product Data Sheet
DBCO-β-Glu-PEG12-Exatecan
Catalog No. A41407
DBCO-β-Glu-PEG12-Exatecan serves as a drug-linker conjugate specifically designed for antibody-drug conjugates (ADCs). This compound acts as a potent inhibitor of topoisomerase I, effectively disrupting DNA replication and transcription processes. Its unique structure allows for targeted delivery in therapeutic applications, making it suitable for research in cancer treatment and other malignancies. This reagent provides a valuable tool for the development and optimization of ADC formulations.
Chemical Information
| Catalog Num | A41407 |
|---|---|
| M. Wt | 1833.95 |
| Formula | C92H117FN8O30 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 3025107-83-6 |
| Synonyms | |
| SMILES | O=C(OCC(C=C1)=CC(CNC(CCNC([C@H](CNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)NC(CCCCC(N2C3=CC=CC=C3C#CC4=CC=CC=C4C2)=O)=O)=O)=O)=C1O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]([C@H]5O)C(O)=O)N[C@@H]6C(C7=C8CC6)=C(CN9C%10=CC([C@@]%11(O)CC)=C(COC%11=O)C9=O)C%10=NC7=CC(F)=C8C |
Biological Activity
| Description | DBCO-β-Glu-PEG12-Exatecan serves as a drug-linker conjugate specifically designed for antibody-drug conjugates (ADCs). This compound acts as a potent inhibitor of topoisomerase I, effectively disrupting DNA replication and transcription processes. Its unique structure allows for targeted delivery in therapeutic applications, making it suitable for research in cancer treatment and other malignancies. This reagent provides a valuable tool for the development and optimization of ADC formulations. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
