Product Data Sheet
LacNAc-VC-PAB-MMAE
Catalog No. A41418
LacNAc-VC-PAB-MMAE is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound is specifically engineered for attachment at the N-glycosylation site of Trastuzumab, utilizing WT Endo-S2 for assembly. LacNAc-VC-PAB-MMAE facilitates targeted delivery of cytotoxic agents, enhancing therapeutic efficacy in cancer treatment applications. Its innovative design supports research in ADC optimization and development for improved specificity and reduced systemic toxicity.
Chemical Information
| Catalog Num | A41418 |
|---|---|
| M. Wt | 1541.78 |
| Formula | C74H116N12O23 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2823367-88-8 |
| Synonyms | |
| SMILES | O=C(CO/N=C/[C@H]1O[C@H]([C@@H]([C@H]([C@H]1O)O)O)O[C@H]2[C@@H]([C@H]3N=C(O[C@H]3O[C@@H]2CO)C)O)N[C@H](C(N[C@@H](CCCNC(N)=O)C(NC4=CC=C(COC(N(C)[C@H](C(N[C@H](C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N5CCC[C@H]5[C@@H]([C@H](C(N[C@@H]([C@@H](O)C6=CC=CC=C6)C)=O)C)OC)=O)=O)C(C)C)=O)C(C)C)=O)C=C4)=O)=O)C(C)C |
Biological Activity
| Description | LacNAc-VC-PAB-MMAE is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound is specifically engineered for attachment at the N-glycosylation site of Trastuzumab, utilizing WT Endo-S2 for assembly. LacNAc-VC-PAB-MMAE facilitates targeted delivery of cytotoxic agents, enhancing therapeutic efficacy in cancer treatment applications. Its innovative design supports research in ADC optimization and development for improved specificity and reduced systemic toxicity. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
