Product Data Sheet

SC-VC-PAB-DM1

Catalog No. A41449

main product photo
SC-VC-PAB-DM1 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs), employing DM1 (Mertansine), a potent tubulin inhibitor. This conjugate exhibits significant antitumor activity through targeted delivery, facilitating the precise release of the cytotoxic agent in malignant tissues. SC-VC-PAB-DM1 is suitable for research applications focused on cancer therapeutics and the development of effective ADCs.
Chemical Information
Catalog NumA41449
M. Wt1280.81
FormulaC61H82ClN9O19
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2259318-47-1
Synonyms
SMILESC[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCC(ON6C(CCC6=O)=O)=O)=O)=O)=O)C=C5)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
Biological Activity
DescriptionSC-VC-PAB-DM1 is a drug-linker conjugate designed for antibody-drug conjugates (ADCs), employing DM1 (Mertansine), a potent tubulin inhibitor. This conjugate exhibits significant antitumor activity through targeted delivery, facilitating the precise release of the cytotoxic agent in malignant tissues. SC-VC-PAB-DM1 is suitable for research applications focused on cancer therapeutics and the development of effective ADCs.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.