Product Data Sheet

2-MSP-5-HA-VA-PAB-Exatecan

Catalog No. A41466

main product photo
2-MSP-5-HA-VA-PAB-Exatecan is a drug-linker conjugate specifically designed for antibody-drug conjugates (ADCs). This compound incorporates Exatecan, a potent topoisomerase I inhibitor, linked via a stable spacer. It is utilized in the synthesis of ADCs, enabling targeted delivery of cytotoxic agents to cancer cells, thereby enhancing therapeutic efficacy while minimizing systemic toxicity.
Chemical Information
Catalog NumA41466
M. Wt1005.08
FormulaC51H53FN8O11S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2878440-72-1
Synonyms
SMILESCS(C1=NC=C(C=N1)C#CCCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C2)=CC=C2COC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)(=O)=O
Biological Activity
Description2-MSP-5-HA-VA-PAB-Exatecan is a drug-linker conjugate specifically designed for antibody-drug conjugates (ADCs). This compound incorporates Exatecan, a potent topoisomerase I inhibitor, linked via a stable spacer. It is utilized in the synthesis of ADCs, enabling targeted delivery of cytotoxic agents to cancer cells, thereby enhancing therapeutic efficacy while minimizing systemic toxicity.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.