Product Data Sheet

AcLysValCit-PABC-DMAE-SW-163D

Catalog No. A41490

main product photo
AcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugate designed for antibody-drug conjugates (ADCs). This compound features the natural bis-intercalator SW-163D linked through the AcLysValCitPABC-DMAE moiety, facilitating targeted delivery of cytotoxic agents. It is instrumental in enhancing the efficacy of ADCs by improving specificity and reducing off-target effects in cancer research applications.
Chemical Information
Catalog NumA41490
M. Wt1817.05
FormulaC85H113N19O22S2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2411007-69-5
Synonyms
SMILESC[C@H](NC1=O)C(N([C@H](C(N([C@]2(C(OC[C@@H](NC(C3=C(C=C4C(C=CC=C4)=N3)O)=O)C(N[C@H](C(N(C)[C@@H](CS5)C(N(C)[C@]6(C(OC[C@H]1NC(C7=C(C=C8C(C=CC=C8)=N7)OC(N(CCN(C(OCC9=CC=C(C=C9)NC([C@@H](NC([C@@H](NC([C@@H](CCCCN)NC(C)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)=O)C)C)=O)=O)=O)[C@H](C6)C)=O)=O)C)=O)=O)[C@H](C2)C)C)=O)[C@H]5SC)C)=O
Biological Activity
DescriptionAcLysValCit-PABC-DMAE-SW-163D is a drug-linker conjugate designed for antibody-drug conjugates (ADCs). This compound features the natural bis-intercalator SW-163D linked through the AcLysValCitPABC-DMAE moiety, facilitating targeted delivery of cytotoxic agents. It is instrumental in enhancing the efficacy of ADCs by improving specificity and reducing off-target effects in cancer research applications.
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SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.