Product Data Sheet
PNU-EDA-Gly5
Catalog No. A41508
PNU-EDA-Gly5 is an oligo-glycine linker designed for antibody-drug conjugate (ADC) synthesis, consisting of the DNA topoisomerase I inhibitor PNU-159682 linked to EDA-Gly5. This compound facilitates targeted delivery of cytotoxic agents while maintaining the activity of the payload, making it useful for the development of ADCs aimed at cancer therapies. Researchers can utilize PNU-EDA-Gly5 to explore novel therapeutic strategies in oncology and enhance the efficacy of targeted treatment modalities.
Chemical Information
| Catalog Num | A41508 |
|---|---|
| M. Wt | 954.93 |
| Formula | C43H54N8O17 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1957223-28-7 |
| Synonyms | |
| SMILES | OC1=C2C(C(C3=C(OC)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@]6([H])N7[C@]([C@H](OCC7)OC)([H])O[C@]6([H])[C@@H](O5)C)=C1C[C@](O)(C4)C(NCCNC(CNC(CNC(CNC(CNC(CN)=O)=O)=O)=O)=O)=O |
Biological Activity
| Description | PNU-EDA-Gly5 is an oligo-glycine linker designed for antibody-drug conjugate (ADC) synthesis, consisting of the DNA topoisomerase I inhibitor PNU-159682 linked to EDA-Gly5. This compound facilitates targeted delivery of cytotoxic agents while maintaining the activity of the payload, making it useful for the development of ADCs aimed at cancer therapies. Researchers can utilize PNU-EDA-Gly5 to explore novel therapeutic strategies in oncology and enhance the efficacy of targeted treatment modalities. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
