Product Data Sheet
Maytansine derivative M24
Catalog No. A41538
Maytansine derivative M24 is a potent drug-linker conjugate targeting the development of antibody-drug conjugates (ADCs). It plays a crucial role in synthesizing ADCs, specifically REGN5093-M114, leveraging its mechanism of action for selective cytotoxicity in targeted cancer therapies. This compound is essential for researchers focused on enhancing therapeutic efficacy while minimizing off-target effects in oncology applications.
Chemical Information
| Catalog Num | A41538 |
|---|---|
| M. Wt | 1268.84 |
| Formula | C61H86ClN9O18 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2226467-81-6 |
| Synonyms | |
| SMILES | C[C@]12[C@H]([C@@H]([C@@H]3C[C@]([C@@H](/C=C/C=C(CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CCN(C)C(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@@H](NC(CCCCC(O)=O)=O)C(C)C)=O)=O)C=C5)=O)=O)=O)=O)C)=C(C(OC)=C4)Cl)\C)OC)(NC(O3)=O)O)C)O1 |
Biological Activity
| Description | Maytansine derivative M24 is a potent drug-linker conjugate targeting the development of antibody-drug conjugates (ADCs). It plays a crucial role in synthesizing ADCs, specifically REGN5093-M114, leveraging its mechanism of action for selective cytotoxicity in targeted cancer therapies. This compound is essential for researchers focused on enhancing therapeutic efficacy while minimizing off-target effects in oncology applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
