Product Data Sheet
Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan
Catalog No. A41570
Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan is a linker utilized for the development of antibody-drug conjugates (ADCs). This compound facilitates the conjugation of cytotoxic agents to target antibodies, enhancing selective delivery to tumor cells. ADCs synthesized with Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan demonstrate significant antitumor efficacy both in vitro and in vivo, making it a valuable reagent for cancer research and therapeutic applications.
Chemical Information
| Catalog Num | A41570 |
|---|---|
| M. Wt | 1074.12 |
| Formula | C55H60FN9O13 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2578019-72-2 |
| Synonyms | |
| SMILES | O=C(C1CCC(CC1)CN2C(C=CC2=O)=O)NCC(NCC(N[C@@H](CC3=CC=CC=C3)C(NCC(NCO[C@@H](C)C(N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95)=O)=O)=O)=O)=O |
Biological Activity
| Description | Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan is a linker utilized for the development of antibody-drug conjugates (ADCs). This compound facilitates the conjugation of cytotoxic agents to target antibodies, enhancing selective delivery to tumor cells. ADCs synthesized with Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan demonstrate significant antitumor efficacy both in vitro and in vivo, making it a valuable reagent for cancer research and therapeutic applications. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
